Botox relaxes the muscles in the application site, by preventing their contraction. With this effect, the subcutaneous muscles that cause wrinkles get relaxed, resulting in a smoother appearance. Botox begins to show its effect 48 hours after its injection, and its full effect appears at the end of the first week. On the other hand, the effect of Botox is not permanent. The procedure should be repeated at 4 to 5 weeks intervals. As regular applications continue, the intervals of injections will become longer. There are no known side effects of Botox that have been identified.
Fillers are used to eliminate grooves or deep wrinkles that cause shadows on the face. The groove between the nose and the upper lip, and the Marionette lines are the most common application sites. The deep frown lines and the forehead region are the areas, where fillers are used successfully.
Botox and filler injections are outpatient treatments. Since filler injections may be a little bit more painful than Botox injection, local anesthetic creams and injections can be used during filling the filling process in patients with low pain thresholds.